{"id":44799,"date":"2023-12-05T08:29:21","date_gmt":"2023-12-05T05:29:21","guid":{"rendered":"https:\/\/www.turkishpost.net\/ar\/?p=44799"},"modified":"2023-12-05T08:29:21","modified_gmt":"2023-12-05T05:29:21","slug":"yogurt-depresyondan-koruyormus","status":"publish","type":"post","link":"https:\/\/www.turkishpost.net\/ar\/yogurt-depresyondan-koruyormus\/","title":{"rendered":"Yo\u011furt depresyondan koruyormu\u015f"},"content":{"rendered":"

(The Turkish Post) – <\/strong>Ara\u015ft\u0131rmac\u0131lar, Laktobasil\u2019in stres y\u00f6netiminde oyna\u011f\u0131 \u00f6nemli rol\u00fc ve potansiyel olarak depresyon ve anksiyeteyi \u00f6nledi\u011fini ortaya \u00e7\u0131kard\u0131.<\/p>\n

Virginia \u00dcniversitesi (UVA) T\u0131p Fak\u00fcltesi\u2019nden ara\u015ft\u0131rmac\u0131lar, fermente g\u0131dalar\u0131n ve yo\u011furdun i\u00e7erdi\u011fi bir bakteri olan Laktobasil\u2019in, bedenimizin stresle ba\u015fa \u00e7\u0131kmas\u0131na ve depresyon ve kayg\u0131y\u0131 \u00f6nlemeye nas\u0131l yard\u0131mc\u0131 olabildi\u011fini ke\u015ffettiler. Ula\u015f\u0131lan bulgular anksiyete, depresyon ve benzeri zihinsel sa\u011fl\u0131k sorunlar\u0131n\u0131 iyile\u015ftirebilecek yeni tedavilerin \u00f6n\u00fcn\u00fc a\u00e7\u0131yor.<\/p>\n

Z\u0130H\u0130NSEL SA\u011eLIK \u00dcZER\u0130NDEK\u0130 ETK\u0130S\u0130<\/strong><\/p>\n

UVA\u2019dan Dr. Alban Gaultier, ve meslekta\u015flar\u0131 taraf\u0131ndan ger\u00e7ekle\u015ftirilen yeni ara\u015ft\u0131rma fazlas\u0131yla ilgi \u00e7ekici \u00e7\u00fcnk\u00fc Laktobasil\u2019in oynad\u0131\u011f\u0131 rol\u00fc tespit ederek onu v\u00fccudumuzda do\u011fal bi\u00e7imde ya\u015fayan t\u00fcm ba\u015fka mikroorganizmalardan ay\u0131r\u0131yor. Bu organizmalar toplu olarak \u2018mikrobiyota\u2019 ad\u0131yla biliniyor ve bilim insanlar\u0131 onlar\u0131 hastal\u0131klarla m\u00fccadele etmek ve sa\u011fl\u0131\u011f\u0131m\u0131z\u0131 geri kazanmak do\u011frultusunda git gide daha fazla ara\u015ft\u0131r\u0131yor. UVA\u2019dan yay\u0131nlanan yeni ara\u015ft\u0131rma, bu u\u011fra\u015fta ileriye do\u011fru at\u0131lan b\u00fcy\u00fck bir ad\u0131m\u0131 temsil ediyor ve bilim insanlar\u0131na hem zihinsel hem de fiziksel alanda \u00e7ok farkl\u0131 hastal\u0131klara kar\u015f\u0131 yeni tedavi ve \u00e7arelerin geli\u015ftirilmesini kolayla\u015ft\u0131rabilecek her bir mikrobun rol\u00fcn\u00fc anlamalar\u0131 i\u00e7in yenilik\u00e7i ve yeni bir yakla\u015f\u0131m sunuyor.<\/p>\n

UVA N\u00f6robilim Anabilim Dal\u0131, Beyin \u0130mm\u00fcnoloji ve Glia Merkezi (BIG Merkez) ve \u00dcniversiteleraras\u0131 Mikrobiyom Giri\u015fimi\u2019nde \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcren Gaultier, \u201cYapt\u0131\u011f\u0131m\u0131z ke\u015fif, ba\u011f\u0131rsakta ya\u015fayan Laktobasil\u2019in ba\u011f\u0131\u015f\u0131kl\u0131k sistemini d\u00fczenleyerek duygudurum bozukluklar\u0131 \u00fczerinde hangi etkileri yaratt\u0131\u011f\u0131n\u0131 a\u00e7\u0131\u011fa \u00e7\u0131kard\u0131\u201d dedi: \u201cGer\u00e7ekle\u015ftirdi\u011fimiz ara\u015ft\u0131rma, anksiyete ve depresyon hususlar\u0131nda fazlas\u0131yla ihtiya\u00e7 duyulan tedavi ara\u00e7lar\u0131n\u0131 ke\u015ffetmenin yolunu a\u00e7abilir.\u201d<\/p>\n

M\u0130KROB\u0130YATA-DEPRESYON \u0130L\u0130\u015eK\u0130S\u0130<\/strong><\/p>\n

Ba\u011f\u0131rsaklar\u0131m\u0131z do\u011fal haliyle pek \u00e7ok bakteri, mantar ve vir\u00fcse ev sahipli\u011fi yapar. \u0130\u00e7imizde ve \u00fczerimizde ya\u015fayan mikroorganizmalar\u0131n say\u0131s\u0131 bedenimizdeki h\u00fccrelerden fazlad\u0131r. Bu kula\u011fa mide buland\u0131r\u0131c\u0131, hatta kayg\u0131land\u0131r\u0131c\u0131 gelebilir; buna kar\u015f\u0131n, bilim insanlar\u0131 bu k\u00fc\u00e7\u00fck organizmalar\u0131n ve aralar\u0131ndaki sonsuz etkile\u015fimlerin ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin yan\u0131 s\u0131ra zihinsel sa\u011fl\u0131k ve ya\u015fam kalitemizin pek \u00e7ok ba\u015fka y\u00f6n\u00fc a\u00e7\u0131s\u0131ndan hayati \u00f6neme sahip oldu\u011funu gittik\u00e7e daha fazla fark ettiler. Hastal\u0131k, k\u00f6t\u00fc beslenme ya da \u00f6teki sebeplerden kaynaklanan mikrobiyota sorunlar\u0131n\u0131n pek \u00e7ok sa\u011fl\u0131k sorununu k\u00f6t\u00fcle\u015ftirdi\u011fi ve hatta kanserin bedende yay\u0131lmas\u0131na yol a\u00e7t\u0131\u011f\u0131 biliniyor. Bundan \u00f6t\u00fcr\u00fc, ara\u015ft\u0131rmac\u0131lar son y\u0131llarda mikrobiyotay\u0131 mercek alt\u0131na alarak hastal\u0131klara kar\u015f\u0131 m\u00fccadele potansiyeli hususunda a\u015f\u0131r\u0131 derecede heyecanland\u0131lar.<\/p>\n

Ba\u011f\u0131rsak floras\u0131n\u0131 \u2018probiyotik\u2019 diye bilinen yararl\u0131 bakterilerle y\u00f6nlendirmeyi ama\u00e7layan ilk giri\u015fimler karma\u015f\u0131k neticeler ortaya \u00e7\u0131kard\u0131. Kar\u015f\u0131m\u0131zdaki sorunun b\u00fcy\u00fck b\u00f6l\u00fcm\u00fc mikrobiyomun karma\u015f\u0131kl\u0131\u011f\u0131ndan kaynaklan\u0131yor. Her birimizin i\u00e7inde 39 trilyon mikroorganizma bulundu\u011fu tahmin ediliyor; h\u00e2l b\u00f6yleyken, -t\u00fcm \u00f6teki mikroorganizma ve konak\u00e7\u0131lar\u0131yla nas\u0131l etkile\u015fime girdikleri bir yana- belirli bir bakteri ya da mantar t\u00fcr\u00fcn\u00fcn sadece ne yapt\u0131\u011f\u0131n\u0131 anlamaya \u00e7al\u0131\u015fmak bile, bir kumsalda bulunan kum tanelerini saymaya \u00e7al\u0131\u015fmak gibidir.<\/p>\n

YEN\u0130L\u0130K\u00c7\u0130 B\u0130R YAKLA\u015eIM<\/strong><\/p>\n

Gaultier ve ekibi, \u00f6zel olarak Laktobasillere odaklanarak yenilik\u00e7i bir yakla\u015f\u0131m benimsedi. Gaultier\u2019in laboratuvar\u0131nda ger\u00e7ekle\u015ftirilen daha \u00f6nceki ara\u015ft\u0131rmalar, bakterilerin laboratuvar farelerinde depresyonu tersine \u00e7evirebilece\u011fini g\u00f6sterdi ve bu son derece umut verici bir bulguydu. Bununla birlikte, ara\u015ft\u0131rmac\u0131lar\u0131n bunun nas\u0131l oldu\u011funu anlamalar\u0131 gerekiyordu: \u201cDaha eski ara\u015ft\u0131rmalar\u0131m\u0131zdan, Laktobasil\u2019in duygudurum sorunlar\u0131n\u0131 sa\u011faltma noktas\u0131nda yararl\u0131 oldu\u011funu ve psikolojik stresin ard\u0131ndan yok oldu\u011funu biliyorduk; buna kar\u015f\u0131n, altta yatan sebepler, \u00f6ncelikle mikrobiyomun incelenmesine ili\u015fkin teknik g\u00fc\u00e7l\u00fckler y\u00fcz\u00fcnden belirsizli\u011fini korudu.\u201d<\/p>\n

Gaultier ve ara\u015ft\u0131rma ekibi, depresyon ara\u015ft\u0131rmalar\u0131n\u0131 iki Laktobasil ve alt\u0131 farkl\u0131 bakteri alt t\u00fcr\u00fcn\u00fc i\u00e7eren \u2018De\u011fi\u015ftirilmi\u015f Schaedler Floras\u0131\u2019 ad\u0131 verilen bir bakteri kar\u0131\u015f\u0131m\u0131 kullanarak s\u00fcrd\u00fcrmeye karar verdi. Ekip, ender zamanlarda kullan\u0131lan bu bakteri toplulu\u011fu arac\u0131l\u0131\u011f\u0131yla, antibiyotik ihtiyac\u0131n\u0131 yok ederek Laktobasil bar\u0131nd\u0131ran ve bar\u0131nd\u0131rmayan fareler \u00fcretmeyi ba\u015fard\u0131.<\/p>\n

\u00c7I\u011eIR A\u00c7ICI BULGULAR<\/strong><\/p>\n

\u015e\u00fcphesiz, \u2018De\u011fi\u015ftirilmi\u015f Schaedler Floras\u0131\u2019 heyecan verici sonu\u00e7lar ortaya koydu. Gaultier ve meslekta\u015flar\u0131, Laktobasillerin davran\u0131\u015flar\u0131m\u0131z\u0131 nas\u0131l etkiledi\u011fini ve bakteri eksikli\u011finin depresyon ve kayg\u0131y\u0131 nas\u0131l k\u00f6t\u00fcle\u015ftirebildi\u011fini eksiksiz bi\u00e7imde izah edebildiler. \u2018Lactobaccillacea\u2019 ailesinde yer alan Laktobasillerin, v\u00fccudun stres kar\u015f\u0131s\u0131nda verdi\u011fi tepkiyi d\u00fczenleyen ve depresyonu \u00f6nlemeye yard\u0131m eden \u2018interferon gama\u2019 adl\u0131 bir ba\u011f\u0131\u015f\u0131kl\u0131k unsurunun seviyesini muhafaza etti\u011fini ke\u015ffettiler.<\/p>\n

Bu bilgilere ula\u015fan ara\u015ft\u0131rmac\u0131lar, Lactobasil\u2019in kritik bir rol oynad\u0131\u011f\u0131 depresyon ve di\u011fer zihin sa\u011fl\u0131\u011f\u0131 sorunlar\u0131n\u0131 \u00f6nlemek ve bunlar\u0131 tedavi etmek do\u011frultusunda yeni yollar ke\u015ffetmeye haz\u0131rlar. Mesela, depresyonla m\u00fccadele eden (ya da depresyon tehdidi alt\u0131nda olan) hastalar, gelecekte \u00f6zel olarak haz\u0131rlanan ve faydal\u0131 Laktobasil d\u00fczeylerini uygun hale getiren probiyotik takviyeleri kullanabilirler.<\/p>\n

Ara\u015ft\u0131rmac\u0131 Andrea R. Merchak, \u201cUla\u015ft\u0131\u011f\u0131m\u0131z bu sonu\u00e7larla, yeni tedaviler alan\u0131nda ke\u015fiflere h\u0131z kazand\u0131rmas\u0131 gereken probiyotiklerin geli\u015fimini iyile\u015ftirmek i\u00e7in yeni ara\u00e7lara sahibiz\u201d diyor: \u201cEn \u00f6nemli husus \u015fu ki, art\u0131k anksiyete ve depresyonu \u00f6nleme ve tedavi etme ba\u011flam\u0131nda sa\u011fl\u0131kl\u0131 bir Laktobasil ve \/ veya interferon gama seviyesini nas\u0131l koruyabilece\u011fimizi anlayabiliriz.\u201d<\/p>\n

UVA\u2019ya ba\u011fl\u0131 bilim insanlar\u0131, bulgular\u0131n\u0131 \u2018Brain Behavior and Immunity\u2019 adl\u0131 dergide yay\u0131nlad\u0131.<\/p>\n","protected":false},"excerpt":{"rendered":"

(The Turkish Post) – Ara\u015ft\u0131rmac\u0131lar, Laktobasil\u2019in stres y\u00f6netiminde oyna\u011f\u0131 \u00f6nemli rol\u00fc ve potansiyel olarak depresyon ve anksiyeteyi \u00f6nledi\u011fini ortaya \u00e7\u0131kard\u0131. Virginia \u00dcniversitesi (UVA) T\u0131p Fak\u00fcltesi\u2019nden ara\u015ft\u0131rmac\u0131lar, fermente g\u0131dalar\u0131n ve yo\u011furdun i\u00e7erdi\u011fi bir bakteri olan Laktobasil\u2019in, bedenimizin stresle ba\u015fa \u00e7\u0131kmas\u0131na ve depresyon ve kayg\u0131y\u0131 \u00f6nlemeye nas\u0131l yard\u0131mc\u0131 olabildi\u011fini ke\u015ffettiler. Ula\u015f\u0131lan bulgular anksiyete, depresyon ve benzeri zihinsel […]<\/p>\n","protected":false},"author":5,"featured_media":44800,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"SciTech Daily","source_url":"Yaz\u0131n\u0131n orijinali SciTech Daily sitesinden al\u0131nm\u0131\u015ft\u0131r. (\u00c7eviren: Tarkan Tufan)","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"topbottom","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"0","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"0","show_post_reading_time":"1","post_reading_time_wpm":"300","show_zoom_button":"1","zoom_button_out_step":"4","zoom_button_in_step":"4","show_post_tag":"1","show_prev_next_post":"0","show_popup_post":"1","number_popup_post":"2","show_author_box":"1","show_post_related":"1","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-715","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trending","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"2285","hide":"2285"},"jnews_override_bookmark_settings":{"override_bookmark_button":"0","override_show_bookmark_button":"0"},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"footnotes":""},"categories":[2285,1],"tags":[2816,10284,315,10282,10283],"class_list":["post-44799","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji","category-son-haberler","tag-depresyon","tag-laktobasil","tag-ust-manset","tag-virginia-universitesi","tag-yogurt"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/44799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/comments?post=44799"}],"version-history":[{"count":0,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/44799\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media\/44800"}],"wp:attachment":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media?parent=44799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/categories?post=44799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/tags?post=44799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}