{"id":42380,"date":"2023-11-24T12:28:24","date_gmt":"2023-11-24T09:28:24","guid":{"rendered":"https:\/\/www.turkishpost.net\/ar\/?p=42380"},"modified":"2023-11-24T12:28:24","modified_gmt":"2023-11-24T09:28:24","slug":"kemik-ve-dis-yenilenmesini-hizlandiran-biyomateryal-gelistirildi","status":"publish","type":"post","link":"https:\/\/www.turkishpost.net\/ar\/kemik-ve-dis-yenilenmesini-hizlandiran-biyomateryal-gelistirildi\/","title":{"rendered":"Kemik ve di\u015f yenilenmesini h\u0131zland\u0131ran biyomateryal geli\u015ftirildi"},"content":{"rendered":"

(The Turkish Post) –<\/strong> Brezilya’daki Sao Paulo Devlet \u00dcniversitesi Botucatu Biyobilimler Enstit\u00fcs\u00fc’nden (IBB-UNESP) ara\u015ft\u0131rmac\u0131lar, kemik greftleri ve di\u015f implantlar\u0131 da dahil olmak \u00fczere \u00e7e\u015fitli tedavileri iyile\u015ftirmek amac\u0131yla kemik dokusunu yenileyebilen benzersiz bir biyomateryal geli\u015ftirdiklerini duyurdu.<\/p>\n

HASTANEDE YATI\u015e S\u00dcRES\u0130N\u0130 KISALTAB\u0130L\u0130R<\/strong><\/p>\n

Donan\u0131mhaber’in de aktard\u0131\u011f\u0131 gibi yap\u0131lan ara\u015ft\u0131rman\u0131n amac\u0131, kemik dokusuyla ilgili operasyonlarla ili\u015fkili ola\u011fan yan etkilerinin \u00f6nlenmesi, tedavi maliyetlerinde d\u00fc\u015f\u00fc\u015fe, hastanede kal\u0131\u015f s\u00fcrelerinde azalmaya ve hastalar\u0131n iyile\u015fme oranlar\u0131nda art\u0131\u015fa yol a\u00e7abilecek bir malzeme geli\u015ftirmekti. Bu hedeflere ula\u015f\u0131lmas\u0131 i\u00e7in malzemenin hem klinik deneylerde hem de uygulamalarda g\u00fcvenli ve etkili kal\u0131rken kemik yap\u0131s\u0131n\u0131n karma\u015f\u0131kl\u0131\u011f\u0131n\u0131 taklit etmesi gerekiyor.<\/p>\n

Ara\u015ft\u0131rmac\u0131lardan olan Willian Fernando Zambuzzi, \u201cVerilerimiz ilk kez hipoksiye (dokudaki d\u00fc\u015f\u00fck oksijen seviyeleri) dayanarak kemik dokusunu yenileme potansiyeline sahip yeni bir biyomimetik malzemeye sahip olabilece\u011fimize dair yeterli kan\u0131t \u00fcretti.\u201d ifadelerini kulland\u0131.<\/p>\n

Yeni malzemenin kemik dokusu gerektiren mevcut yakla\u015f\u0131mlarda b\u00fcy\u00fck bir geli\u015fme sa\u011flayaca\u011f\u0131 d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n

G\u00fcn\u00fcm\u00fczde, k\u0131r\u0131\u011f\u0131 olan veya t\u00fcm\u00f6r rezeksiyonuna ihtiya\u00e7 duyan hastalar i\u00e7in kullan\u0131lan greftleme teknikleri genellikle hastan\u0131n kendi kemik par\u00e7alar\u0131n\u0131n kullan\u0131lmas\u0131n\u0131 i\u00e7eriyor. Ancak, bu prosed\u00fcrler i\u00e7in hayati \u00f6nem ta\u015f\u0131yan otojen malzemenin elde edilmesi, enfeksiyon riski ta\u015f\u0131yan ve daha uzun iyile\u015fme s\u00fcrelerine yol a\u00e7an ek bir ameliyat gerektiriyor.<\/p>\n

Yeni malzeme, i\u00e7erdi\u011fi kobalt klor\u00fcr nedeniyle kobalt katk\u0131l\u0131 monetit olarak adland\u0131r\u0131l\u0131yor. Zambuzzi, yeni bulu\u015funa kobalt klor\u00fcr eklemeye karar verdi \u00e7\u00fcnk\u00fc kobalt klor\u00fcr\u00fcn hipoksiyi te\u015fvik etti\u011fi ve v\u00fccudun oksijen eksikli\u011fini telafi etmek i\u00e7in kan damarlar\u0131n\u0131n say\u0131s\u0131n\u0131 art\u0131rmas\u0131na neden oldu\u011fu biliniyor.<\/p>\n

MALZEME G\u00dcVENL\u0130<\/strong><\/p>\n

Yenilik\u00e7i malzemenin, t\u0131bbi cihazlar i\u00e7in birincil biyolojik de\u011ferlendirme standard\u0131na (ISO 10993:5) dayal\u0131 sitotoksisite testine g\u00f6re insan v\u00fccudu i\u00e7in g\u00fcvenli oldu\u011fu rapor edildi. Ayr\u0131ca, ekibin hayvan deneyleri de dahil olmak \u00fczere preklinik modeller kullanarak yapt\u0131\u011f\u0131 daha derinlemesine incelemenin, malzemenin protezler i\u00e7in kaplamalar ve enjekte edilebilir kemik \u00e7imentosu da dahil olmak \u00fczere \u00e7e\u015fitli biyomedikal uygulamalardaki kullan\u0131\u015fl\u0131l\u0131\u011f\u0131 konusunda ba\u015far\u0131l\u0131 oldu\u011fu g\u00f6r\u00fcld\u00fc.<\/p>\n

Bununla birlikte, kobalt miktar\u0131n\u0131n, \u00f6zellikle kemik yenilenmesi alan\u0131nda olmak \u00fczere, gelecekteki biyomedikal kullan\u0131mlar i\u00e7in gerekli olan malzemenin optimum konsantrasyonunun belirlenmesinde \u00e7ok \u00f6nemli bir rol oynad\u0131\u011f\u0131 tespit edildi. Kesin olan bir \u015fey var: Bu bulu\u015f kemik yenilenmesi alan\u0131n\u0131 \u015fekillendirecek ve ortopedik bak\u0131mda sonu\u00e7lar\u0131 iyile\u015ftirmek i\u00e7in yeni olanaklar sunacak.<\/p>\n","protected":false},"excerpt":{"rendered":"

(The Turkish Post) – Brezilya’daki Sao Paulo Devlet \u00dcniversitesi Botucatu Biyobilimler Enstit\u00fcs\u00fc’nden (IBB-UNESP) ara\u015ft\u0131rmac\u0131lar, kemik greftleri ve di\u015f implantlar\u0131 da dahil olmak \u00fczere \u00e7e\u015fitli tedavileri iyile\u015ftirmek amac\u0131yla kemik dokusunu yenileyebilen benzersiz bir biyomateryal geli\u015ftirdiklerini duyurdu. HASTANEDE YATI\u015e S\u00dcRES\u0130N\u0130 KISALTAB\u0130L\u0130R Donan\u0131mhaber’in de aktard\u0131\u011f\u0131 gibi yap\u0131lan ara\u015ft\u0131rman\u0131n amac\u0131, kemik dokusuyla ilgili operasyonlarla ili\u015fkili ola\u011fan yan etkilerinin \u00f6nlenmesi, […]<\/p>\n","protected":false},"author":8,"featured_media":42383,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"Cumhuriyet","source_url":"https:\/\/www.cumhuriyet.com.tr\/bilim-teknoloji\/kemik-ve-dis-yenilenmesini-hizlandiran-biyomateryal-gelistirildi","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"topbottom","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"0","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"0","show_post_reading_time":"1","post_reading_time_wpm":"300","show_zoom_button":"1","zoom_button_out_step":"4","zoom_button_in_step":"4","show_post_tag":"1","show_prev_next_post":"0","show_popup_post":"1","number_popup_post":"2","show_author_box":"1","show_post_related":"1","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-715","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trending","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"107","hide":""},"jnews_override_bookmark_settings":{"override_bookmark_button":"0","override_show_bookmark_button":"0"},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"footnotes":""},"categories":[107,1],"tags":[9745,9746,9743,315,9744],"class_list":["post-42380","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yasam","category-son-haberler","tag-biyomateryal","tag-gelistirildi","tag-kemik","tag-ust-manset","tag-ve-dis"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/42380","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/comments?post=42380"}],"version-history":[{"count":0,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/42380\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media\/42383"}],"wp:attachment":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media?parent=42380"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/categories?post=42380"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/tags?post=42380"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}