{"id":30762,"date":"2023-10-02T13:46:53","date_gmt":"2023-10-02T10:46:53","guid":{"rendered":"https:\/\/www.turkishpost.net\/ar\/?p=30762"},"modified":"2023-10-04T11:46:25","modified_gmt":"2023-10-04T08:46:25","slug":"nobel-fizyoloji-ve-tip-odulu-aciklandi-katalin-kariko-ve-drew-weissmana-verildi","status":"publish","type":"post","link":"https:\/\/www.turkishpost.net\/ar\/nobel-fizyoloji-ve-tip-odulu-aciklandi-katalin-kariko-ve-drew-weissmana-verildi\/","title":{"rendered":"Nobel Fizyoloji ve T\u0131p \u00d6d\u00fcl\u00fc a\u00e7\u0131kland\u0131: Katalin Karik\u00f3 ve Drew Weissman’a verildi"},"content":{"rendered":"

(The Turkish Post) – <\/strong>Bilim d\u00fcnyas\u0131n\u0131n en prestijli \u00f6d\u00fcllerinden olan Nobel Fizyoloji ve T\u0131p \u00d6d\u00fcl\u00fc bu y\u0131l,\u00a0 mRNA COVID -19 a\u015f\u0131lar\u0131n\u0131n geli\u015ftirilmesini sa\u011flayan ke\u015fifleri nedeniyle s\u0131ras\u0131yla Macaristanl\u0131 bilim insan\u0131 Katalin Kariko ve Drew Weismann’a verildi.<\/p>\n

\u00d6d\u00fcl, \u0130sve\u00e7’in Karolinska Enstit\u00fcs\u00fc t\u0131p \u00fcniversitesinin Nobel Meclisi taraf\u0131ndan se\u00e7iliyor ve ayr\u0131ca 11 milyon \u0130sve\u00e7 kronu (yakla\u015f\u0131k 1 milyon dolar) ile birlikte geliyor.<\/p>\n

Kurumdan yap\u0131lan a\u00e7\u0131klamada, “Fizyoloji veya T\u0131p alan\u0131nda 2023 Nobel \u00d6d\u00fcl\u00fc, COVID-19’a kar\u015f\u0131 etkili mRNA a\u015f\u0131lar\u0131n\u0131n geli\u015ftirilmesini sa\u011flayan n\u00fckleozit baz modifikasyonlar\u0131na ili\u015fkin ke\u015fifleri nedeniyle Katalin Karik\u00f3 ve Drew Weissman’a verildi” denildi.<\/p>\n

Kariko, 2022 y\u0131l\u0131na kadar BioNTech’te k\u0131demli ba\u015fkan yard\u0131mc\u0131s\u0131 ve RNA protein replasman\u0131 ba\u015fkan\u0131yd\u0131 ve o zamandan beri \u015firketin dan\u0131\u015fman\u0131 olarak g\u00f6rev yap\u0131yor. Kariko ayr\u0131ca, Macaristan’daki Szeged \u00dcniversitesi’nde profes\u00f6r ve Pennsylvania \u00dcniversitesi Perelman T\u0131p Fak\u00fcltesi’nde yard\u0131mc\u0131 profes\u00f6r olarak g\u00f6rev yap\u0131yor.<\/p>\n

Kariko, daha \u00f6nce, mRNA’n\u0131n herhangi bir terap\u00f6tik kullan\u0131m\u0131na kar\u015f\u0131 b\u00fcy\u00fck bir engel olarak g\u00f6r\u00fclen, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin laboratuvar yap\u0131m\u0131 mRNA’ya kar\u015f\u0131 inflamatuar bir reaksiyon ba\u015flatmas\u0131n\u0131 \u00f6nlemenin bir yolunu bulmu\u015ftu.<\/p>\n

Macar biliim insan\u0131, Perelman School’da a\u015f\u0131 ara\u015ft\u0131rmalar\u0131 alan\u0131nda profes\u00f6r olan Weissman ile birlikte 2005 y\u0131l\u0131nda, mRNA’n\u0131n genetik kodunu yazan molek\u00fcler harfler olan n\u00fckleozitlerde yap\u0131lan ayarlamalar\u0131n, mRNA’y\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin radar\u0131 alt\u0131nda tutabilece\u011fini g\u00f6sterdi.<\/p>\n

Karolinska Enstit\u00fcs\u00fc Nobel Asamblesi \u00fcyesi Rickard Sandberg \u00f6d\u00fcl duyurusunun ard\u0131ndan \u015funlar\u0131 s\u00f6yledi:<\/p>\n

“Bu y\u0131lki Nobel \u00d6d\u00fcl\u00fc, mRNA’n\u0131n ba\u011f\u0131\u015f\u0131kl\u0131k sistemiyle nas\u0131l etkile\u015fime girdi\u011fine dair anlay\u0131\u015f\u0131m\u0131z\u0131 temelden de\u011fi\u015ftiren ve son pandemi s\u0131ras\u0131nda toplum \u00fczerinde b\u00fcy\u00fck bir etkisi olan temel bilim ke\u015fiflerini takdir ediyor”<\/p>\n

T\u0131p \u00f6d\u00fcl\u00fc bu y\u0131lki \u00f6d\u00fcllerin ba\u015flang\u0131c\u0131 olurken, di\u011fer be\u015f \u00f6d\u00fcl de \u00f6n\u00fcm\u00fczdeki g\u00fcnlerde a\u00e7\u0131klanacak.<\/p>\n

NOBEL \u00d6D\u00dcLLER\u0130 HAKKINDA<\/strong><\/p>\n

\u0130lk kez 1901 y\u0131l\u0131nda \u0130sve\u00e7li dinamit mucidi ve zengin i\u015fadam\u0131 Alfred Nobel taraf\u0131ndan olu\u015fturulan \u00f6d\u00fcller bilim, edebiyat ve bar\u0131\u015f alanlar\u0131ndaki ba\u015far\u0131lar\u0131n yan\u0131 s\u0131ra daha sonraki y\u0131llarda ekonomi alan\u0131ndaki ba\u015far\u0131lara da veriliyor.<\/p>\n

\u0130sve\u00e7 Kral\u0131, Nobel’in \u00f6l\u00fcm y\u0131ld\u00f6n\u00fcm\u00fc olan 10 Aral\u0131k’ta Stockholm’de d\u00fczenlenecek bir t\u00f6renle \u00f6d\u00fclleri takdim edecek ve ard\u0131ndan belediye binas\u0131nda g\u00f6rkemli bir ziyafet verilecek.<\/p>\n

Ge\u00e7en y\u0131l\u0131n t\u0131p \u00f6d\u00fcl\u00fc, g\u00fcn\u00fcm\u00fcz insan\u0131n\u0131n soyu t\u00fckenmi\u015f bir akrabas\u0131 olan Neandertal’in genomunu dizilemesi ve daha \u00f6nce bilinmeyen bir insan akrabas\u0131 olan Denisoval\u0131lar\u0131 ke\u015ffetmesi nedeniyle \u0130sve\u00e7li Svante Paabo’ya verildi.<\/p>\n

Ge\u00e7mi\u015fteki di\u011fer \u00f6d\u00fcl sahipleri aras\u0131nda penisilinin ke\u015ffiyle 1945 \u00f6d\u00fcl\u00fcn\u00fc payla\u015fan Alexander Fleming ve insan kan gruplar\u0131n\u0131 ke\u015ffiyle 1930’da Karl Landsteiner yer al\u0131yor.<\/p>\n","protected":false},"excerpt":{"rendered":"

(The Turkish Post) – Bilim d\u00fcnyas\u0131n\u0131n en prestijli \u00f6d\u00fcllerinden olan Nobel Fizyoloji ve T\u0131p \u00d6d\u00fcl\u00fc bu y\u0131l,\u00a0 mRNA COVID -19 a\u015f\u0131lar\u0131n\u0131n geli\u015ftirilmesini sa\u011flayan ke\u015fifleri nedeniyle s\u0131ras\u0131yla Macaristanl\u0131 bilim insan\u0131 Katalin Kariko ve Drew Weismann’a verildi. \u00d6d\u00fcl, \u0130sve\u00e7’in Karolinska Enstit\u00fcs\u00fc t\u0131p \u00fcniversitesinin Nobel Meclisi taraf\u0131ndan se\u00e7iliyor ve ayr\u0131ca 11 milyon \u0130sve\u00e7 kronu (yakla\u015f\u0131k 1 milyon dolar) […]<\/p>\n","protected":false},"author":8,"featured_media":30765,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"Art\u0131 Ger\u00e7ek ","source_url":"https:\/\/artigercek.com\/saglik\/nobel-fizyoloji-ve-tip-odulu-aciklandi-katalin-kariko-ve-drew-weissmana-verildi-267334h","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"topbottom","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"0","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"0","show_post_reading_time":"1","post_reading_time_wpm":"300","show_zoom_button":"1","zoom_button_out_step":"4","zoom_button_in_step":"4","show_post_tag":"1","show_prev_next_post":"0","show_popup_post":"1","number_popup_post":"2","show_author_box":"1","show_post_related":"1","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-715","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trending","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"2285","hide":""},"jnews_override_bookmark_settings":{"override_bookmark_button":"0","override_show_bookmark_button":"0"},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"footnotes":""},"categories":[2285,1],"tags":[7965,1422,7966,7967],"class_list":["post-30762","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji","category-son-haberler","tag-nobel","tag-slider-manset","tag-tip-ve-fziyoloji","tag-verildi"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/30762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/comments?post=30762"}],"version-history":[{"count":0,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/30762\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media\/30765"}],"wp:attachment":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media?parent=30762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/categories?post=30762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/tags?post=30762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}