{"id":16604,"date":"2023-07-18T13:23:40","date_gmt":"2023-07-18T10:23:40","guid":{"rendered":"https:\/\/www.turkishpost.net\/ar\/?p=16604"},"modified":"2023-07-18T14:37:23","modified_gmt":"2023-07-18T11:37:23","slug":"alzheimeri-yavaslatan-ikinci-ilac-abdde-onay-basvurusunda-bulundu","status":"publish","type":"post","link":"https:\/\/www.turkishpost.net\/ar\/alzheimeri-yavaslatan-ikinci-ilac-abdde-onay-basvurusunda-bulundu\/","title":{"rendered":"Alzheimer’\u0131 yava\u015flatan ikinci ila\u00e7 ABD’de onay ba\u015fvurusunda bulundu"},"content":{"rendered":"

(The Turkish Post) –<\/strong> Eli Lilly firmas\u0131, hen\u00fcz deneme a\u015famas\u0131nda olan Alzheimer hastal\u0131\u011f\u0131 ilac\u0131 Donanemab i\u00e7in\u00a0 Amerikan G\u0131da ve \u0130la\u00e7 \u0130daresi’nin (FDA) onay\u0131na ba\u015fvurdu.<\/p>\n

Donanemab, onaylanmas\u0131 halinde hastalar\u0131n zamanlar haf\u0131zalar\u0131n\u0131 kaybetmesine yol a\u00e7an Alzheimer hastal\u0131\u011f\u0131na kar\u015f\u0131 ila\u00e7 Japon ila\u00e7 firmas\u0131 Eisai taraf\u0131ndan \u00fcretilen Lecanemab’den sonraki ikinci ila\u00e7 olacak.<\/p>\n

Ara\u015ft\u0131rmac\u0131lar ilac\u0131n hastal\u0131\u011f\u0131 4 ila 7 ay geciktirebildi\u011fini a\u00e7\u0131klad\u0131. \u00d6zellikle hastal\u0131\u011f\u0131n erken te\u015fhis edildi\u011fi d\u00f6nemlerde kullan\u0131lmas\u0131 halinde etkinli\u011finin \u00e7ok y\u00fckseldi\u011fi vurguland\u0131. 1700 hasta \u00fczerinde yap\u0131lan \u00e7al\u0131\u015fmada sonu\u00e7lar\u0131n ge\u00e7 d\u00f6nemlerde kullan\u0131lan durumlarda ilac\u0131n daha az etkili oldu\u011funu g\u00f6sterdi.<\/p>\n

Lilly N\u00f6roloji Bilimi Ba\u015fkan\u0131 Anne White bulgular\u0131n erken tespit ve te\u015fhisin hastal\u0131\u011f\u0131n ilerleyi\u015fini de\u011fi\u015ftirmek i\u00e7in hayati \u00f6neme sahip oldu\u011funu vurgulad\u0131.<\/p>\n

Lilly ara\u015ft\u0131rmac\u0131lar\u0131ndan Dr. John Sims gazetecilere yapt\u0131\u011f\u0131 a\u00e7\u0131klamada “Nihayet art\u0131k bir umut \u0131\u015f\u0131\u011f\u0131ndan bahsedebiliyoruz,” ifadelerini kullan\u0131d\u0131.<\/p>\n

Hastal\u0131\u011f\u0131 tedavi etmediklerini belirten Sims “Diyabet hastal\u0131\u011f\u0131n\u0131n da biz \u00e7\u00f6z\u00fcm\u00fc yok ama bu hastalar\u0131n anlaml\u0131 tedavi alamayaca\u011f\u0131 anlam\u0131na gelmiyor,” s\u00f6zlerini kulland\u0131.<\/p>\n

Ciddi yan etkileri bulunuyor<\/p>\n

Donanemab baz\u0131 hastalarda ilerlemeyi ciddi \u015fekilde yava\u015flatmay\u0131 ba\u015farsa da ciddi yan etkiler de g\u00f6sterdi.<\/p>\n

Hem Donanemab hem de Lecanemab laboratuvar ortam\u0131nda geli\u015ftirilen antikorlar olup beyindeki amyloid birikimini hedef al\u0131yor. Fakat her ila\u00e7ta da yan etki olarak beyinde \u015fi\u015fkinlik ve kanama riski bulunuyor ve Lilly’nin \u00e7al\u0131\u015fmalar\u0131 3 \u00f6l\u00fcmle ilintili oldu\u011funu ortaya koyuyor.<\/p>\n

Bilim insanlar\u0131 bu ila\u00e7lar\u0131 Alzheimer tedavisi i\u00e7in devrim olarak nitelendiriyor fakat hangi hastalar\u0131n bunu denemeleri gerekti\u011fi ve kar\u015f\u0131l\u0131\u011f\u0131n nas\u0131l bir fayda g\u00f6recekleri hala b\u00fcy\u00fck bir soru i\u015fareti olarak duruyor.<\/p>\n","protected":false},"excerpt":{"rendered":"

(The Turkish Post) – Eli Lilly firmas\u0131, hen\u00fcz deneme a\u015famas\u0131nda olan Alzheimer hastal\u0131\u011f\u0131 ilac\u0131 Donanemab i\u00e7in\u00a0 Amerikan G\u0131da ve \u0130la\u00e7 \u0130daresi’nin (FDA) onay\u0131na ba\u015fvurdu. Donanemab, onaylanmas\u0131 halinde hastalar\u0131n zamanlar haf\u0131zalar\u0131n\u0131 kaybetmesine yol a\u00e7an Alzheimer hastal\u0131\u011f\u0131na kar\u015f\u0131 ila\u00e7 Japon ila\u00e7 firmas\u0131 Eisai taraf\u0131ndan \u00fcretilen Lecanemab’den sonraki ikinci ila\u00e7 olacak. Ara\u015ft\u0131rmac\u0131lar ilac\u0131n hastal\u0131\u011f\u0131 4 ila 7 ay […]<\/p>\n","protected":false},"author":2,"featured_media":16616,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"Euronews","source_url":"https:\/\/tr.euronews.com\/2023\/07\/18\/alzheimeri-yavaslatan-ikinci-ilac-abdde-onay-basvurusunda-bulundu","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"topbottom","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"0","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"0","show_post_reading_time":"1","post_reading_time_wpm":"300","show_zoom_button":"1","zoom_button_out_step":"4","zoom_button_in_step":"4","show_post_tag":"1","show_prev_next_post":"0","show_popup_post":"1","number_popup_post":"2","show_author_box":"1","show_post_related":"1","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-715","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trending","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"107","hide":""},"jnews_override_bookmark_settings":{"override_bookmark_button":"0","override_show_bookmark_button":"0"},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"footnotes":""},"categories":[1,107],"tags":[5127,5130,5128,5129,1422],"class_list":["post-16604","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-son-haberler","category-yasam","tag-alzheimer","tag-alzheimeri-yavaslatan-ilac","tag-donanemab","tag-eli-lilly","tag-slider-manset"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/16604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/comments?post=16604"}],"version-history":[{"count":0,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/posts\/16604\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media\/16616"}],"wp:attachment":[{"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/media?parent=16604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/categories?post=16604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.turkishpost.net\/ar\/wp-json\/wp\/v2\/tags?post=16604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}